Without a steady supply of new players trying to 1v1 them, Toxic Spider Queens of Kessex are known to experience bouts of great depression, going as far as attempting to drown themselves. :
Guild Wars 2 : Core Guardian - Solo Champion Toxic Spider Queen in Kessex Hills (00:25) - YouTube
The Spider Queen - Guild Wars 2 Wiki (GW2W)
Undergrowth Spider Queen - Guild Wars 2 Wiki (GW2W)